反应详情

The title compound was synthesized in analogy to Example 89 from N-(3-chloro-4-fluorophenyl)-6,7,8,9-tetrahydro-5H-pyrimido[5′,4′:4,5]thieno[2,3-c]azepin-4-amine from Example 81A (160 mg, 80% purity, 0.37 mmol) and (2E)-4-(dimethylamino)but-2-enoic acid hydrochloride from Example 1A (85 mg, 0.51 mmol) to yield 12 mg (7%).

1. customto yield 12 mg (7%)