反应详情

The title compound was synthesized in analogy to Example 89 from N-(3,4-dichlorophenyl)-6,7,8,9-tetrahydro-5H-pyrimido[5′,4′:4,5]thieno[2,3-c]azepin-4-amine from Example 82A (100 mg, 0.27 mmol) and (2E)-4-[methyl(1-methylethyl)amino]but-2-enoic acid hydrochloride from Example 2A (74 mg, 0.38 mmol) to yield 71 mg (50%).

1. customto yield 71 mg (50%)