HuagongsheHuagongshe Chemistry Print Report · For research reference only
(E)-3-[trans-4-(trans-4-propylcyclohexyl)cyclohexyl]acrylic acid ethyl ester → 3-(4'-Propyl-bicyclohexyl-4-yl)-propionic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (E)-3-[trans-4-(trans-4-propylcyclohexyl)cyclohexyl]acrylic acid ethyl ester | HCID 59289066 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-(4'-Propyl-bicyclohexyl-4-yl)-propionic acid ethyl ester | HCID 59289074 | — |
Reaction Steps
(E)-3-(4′-Propyl-bicyclohexyl-4-yl)acrylic acid ethyl ester is hydrogenated in THF in the presence of palladium on charcoal. After 1 eq. of hydrogen has been consumed the catalyst is filtered off, the solvent is evaporated and the residue is filtered through silica yielding 3-(4′-propyl-bicyclohexyl-4-yl)-propionic acid ethyl ester as a colourless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08372307B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-396de578a3024c949f759ad8625a62f9 |
| Source note | uspto-grants-2013_02 |