HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 2-(Benzyloxy)benzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2-Benzyloxybenzoic acid | HCID 1810581 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 2-(Benzyloxy)benzoyl chloride | HCID 10999355 | 79.07% |
Reaction Steps
To a suspension of 78 (3.1 g, 13.6 mmol) in dry toluene (150 ml)was added SOCl2 (12.9 g, 109.1 mmol). The mixture was reflux for 8 h and evaporated to give 83 as yellow liquid to use directly in the next step. (2.55 g, 10.3 mmol). Yield: 79.07%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08524740B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-823eafc0fd1c4645ba8585c254f1e3b4 |
| Source note | uspto-grants-2013_09 |