Chloroform methanol ammonia → HCID 178465563, compound

Participants

Reaction Steps

Prepared analogously to Example 5, starting from 2-[(3-(imidazol-1-yl)-phenyl]-3-benzyloxy-6-[(1-iminoethyl)amino]-4H-1-benzopyran-4-one dihydrochloride. Yield: 90%; m.p.: 281.0-281.5° C. TLC (80/20/2 Chloroform/Methanol/Ammonia) Rf: 0.32; Elem. anal.: C20H16N4O3.2HCl, Theory: C, 55.44; H, 4.19; N, 12.93. Found: C, 53.05; H, 4.34; N, 12.18. 1H-NMR (d6-DMSO): 11.83 (s broad, 1H), 10.30 (s, 1H), 9.75 (m, 2H), 8.73 (s broad, 1H), 8.46 (m, 2H), 8.38 (m, 1H), 8.07-7.75 (m, 6H), 2.41 (s, 3H).

Provenance & Evidence