Benzoic acid, 3-(chlorosulfonyl)- → HCID 66797495, compound

Participants

Reaction Steps

A stirred solution of 3-amino-propionic acid cyclohexyloxycarbonylmethyl ester (step 2) (2.30 g, 10.03 mmol) in DCM (200 ml) at RT was treated with 3-chlorosulfonyl-benzoic acid (3.64 g, 16.50 mmol) followed by N,N-diisopropylethylamine (3.04 ml, 17.45 mmol). The resulting mixture was stirred at RT for 1 h. The reaction mixture was washed with 2N HCl (200 ml), dried over MgSO4 and concentrated in vacuo to afford the title compound; LC-MS Rt 1.34 mins; 414.2 [M+H]+, Method 2minLC_v002.

Provenance & Evidence