HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 7-Methoxy-2H-1,3-benzodioxole-5-carbonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 7-Methoxy-2H-1,3-benzodioxole-5-carboxylic acid | HCID 607309 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 7-Methoxy-2H-1,3-benzodioxole-5-carbonyl chloride | HCID 45081255 | — |
Reaction Steps
3,4-Methylenedioxy-5-methoxybenzoic acid (39.23 g, 0.2 mol) was dissolved in dry benzene, thionyl chloride 47.6 g (28.8 ml, 0.4 mol) was added under stirring, the resulting solution was refluxed for 15 hr, then the solvent and excessive thionyl chloride were removed by distillation under reduced pressure to give pure 3,4-methylenedioxy-5-methoxy-benzoyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08524744B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-0d74cf3a0a884f289676c7264a4288e5 |
| Source note | uspto-grants-2013_09 |