Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 386718Generated: October 30, 2026

Benzyl 3-(4-hydroxyphenyl)propanoate → 3-(4-tert-Butoxycarbonylmethoxy-phenyl)-propionic acid benzyl ester

https://huagongshe.com/reaction/386718

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl 3-(4-hydroxyphenyl)propanoateHCID 14211262—
Reactant3-(4-tert-Butoxycarbonylmethoxy-3-chloro-phenyl)-propionic acid benzyl esterHCID 66797513—
Product3-(4-tert-Butoxycarbonylmethoxy-phenyl)-propionic acid benzyl esterHCID 66798017—

Reaction Steps

This compound was prepared analogously to 3-(4-tert-butoxycarbonylmethoxy-3-chloro-phenyl)-propionic acid benzyl ester (Int. B step 2) by replacing 3-(3-chloro-4-hydroxy-phenyl)-propionic acid benzyl ester with 3-(4-hydroxy-phenyl)-propionic acid benzyl ester (commercially available).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08372845B2
Source datasetuspto-grants-2013_02
ORD IDord-d0bcf720817b4aec8b14ca46036a3699
Source noteuspto-grants-2013_02