HCID 67188704, compound → HCID 86643376, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of {4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl]phenyl}methanol (1 g) in methylene chloride (30 mL), activated manganese oxide (1.8 g) was added, and the mixture was then heated and stirred for 3 hours at 40° C. After filtration of the reaction mixture through Celite, the resultant filtrate was concentrated under reduced pressure to yield 4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl]benzaldehyde (0.8 g).

Provenance & Evidence