Acetic Anhydride → HCID 178418538, compound

HRID 3868Notes

Reaction equation

HRID 3868 reaction equation
[CH3:1][N:2]([CH3:20])[C:3]1[CH:8]=[C:7]([NH2:9])[CH:6]=[CH:5][C:4]=1[C:10]1[N:11]=[C:12]2[CH:17]=[CH:16][C:15](=[O:18])[N:14]=[C:13]2[N:19]=1.[C:21](OC(=O)C)(=[O:23])[CH3:22]>>[CH3:1][N:2]([CH3:20])[C:3]1[CH:8]=[C:7]([NH:9][C:21]([CH3:22])=[O:23])[CH:6]=[CH:5][C:4]=1[C:10]1[N:19]=[C:13]2[NH:14][C:15](=[O:18])[CH2:16][CH:17]=[C:12]2[N:11]=1

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 201532892-(2-Dimethylamino-4-amino-phenyl)imidazo[4,5-b]pyridin-5-one

Product 1

HCID 178418538HCID 178418538, compound

Procedure

A quantity of 0.6 gm of 2-(2-dimethylamino-4-amino-phenyl)imidazo[4,5-b]pyridin-5-one is refluxed with 20 ml of acetic anhydride for 30 minutes. After evaporation, 10 ml of concentrated ammnoia and then 20 ml of ice are added. The product precipitated is suction filtered and washed with water.

Workup

  1. customAfter evaporation, 10 ml of concentrated ammnoia
  2. addition20 ml of ice are added
  3. customThe product precipitated
  4. filtrationfiltered
  5. washwashed with water

Sources & evidence

ORD record
ord-f2c701250f51434a8eabd6294b537cef
Source dataset
uspto-grants-1988_02
Patent number
US04722929

Reaction notes

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