HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → {2'-[(Benzyl-ethyl-carbamoyloxy)-methyl]-6-methoxy-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | {2'-[(Benzyl-ethyl-carbamoyloxy)-methyl]-6-methoxy-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid ethyl ester | HCID 67431340 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | {2'-[(Benzyl-ethyl-carbamoyloxy)-methyl]-6-methoxy-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid | HCID 45280407 | — |
Reaction Steps
{2′-[(Benzyl-ethyl-carbamoyloxy)-methyl]-6-methoxy-4′-trifluoromethyl-biphenyl-3-yl}-acetic acid ethyl ester (0.85 mmol) was dissolved in MeOH (5 mL) and hydrolyzed with 1N aqueous NaOH (0.85 mL, 0.85 mmol) to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08524748B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-d3ce45dc99b94c8d83b1b00fba3ba668 |
| Source note | uspto-grants-2013_09 |