HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-Phenylpiperazine → 1-phenyl-4-(3-(1,5-diphenyl-1H-pyrazol-3-yl)propyl)piperazine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-Phenylpiperazine | HCID 7096 | — |
| Edukt | Diisopropylethylamine | HCID 81531 | — |
| Edukt | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Edukt | 3-(1,5-diphenyl-1H-pyrazol-3-yl)propanal | HCID 42631135 | — |
| Produkt | 1-phenyl-4-(3-(1,5-diphenyl-1H-pyrazol-3-yl)propyl)piperazine | HCID 25064845 | — |
Reaktionsschritte
100 mg (94%) of target compound was obtained by using a method same as in Example 1 by using 3-(1,5-diphenyl-1H-pyrazol-3-yl)propanal (76 mg, 0.275 mmol), 1-phenylpiperazine (0.038 mL, 0.250 mmol), DIPEA (44 mL, 0.250 mmol) and NaBH(OAc)3 (185 mg, 0.875 mmol).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08372844B2 |
| Quelldatensatz | uspto-grants-2013_02 |
| ORD ID | ord-edcc087a8e2a4133bbd23c1a4077b362 |
| Quellennotiz | uspto-grants-2013_02 |