HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 59332581, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1-(1,1-Dimethylethyl) 4-fluoro-2,3-dihydro-1H-indole-1,7-dicarboxylate | HCID 66746715 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 59332581 | HCID 59332581 | — |
Reaction Steps
A solution of 1 M HCl (1 mL, 1 mmol) was added to a solution of 1-{[(1,1-Dimethylethyl)oxy]carbonyl}-4-fluoro-2,3-dihydro-1H-indole-7-carboxylic acid (50 mg, x mmol) in DCM at room temperature. The reaction was stirred for 2 h, and additional 1 M HCl (1 mL, 1 mmol) was added. The reaction was stirred overnight, and the mixture was evaporated and dried under high vacuum, giving the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08372875B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-87f98432cffb419290a7cdece8a942a1 |
| Source note | uspto-grants-2013_02 |