HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → [(5-Bromothiophen-2-yl)methyl]dimethylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | Methanol | HCID 887 | — |
| Reactant | 1-[(5-Bromo-2-thienyl)methyl]pyrrolidine | HCID 59332758 | — |
| Product | [(5-Bromothiophen-2-yl)methyl]dimethylamine | HCID 59332723 | 93% |
Reaction Steps
The above procedure to make 1-[(5-bromo-2-thienyl)methyl]pyrrolidine was repeated except using 2 M dimethylamine in methanol (0.75 mL, 1.5 mmol) to afford 204 mg (93%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08372875B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-96e9d60ad81b46bab749d344d6b46473 |
| Source note | uspto-grants-2013_02 |