HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylacetylene → 1-phenethyl-5-phenyl-1H-1,2,3-triazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylacetylene | HCID 10821 | — |
| Reactant | Benzene, (2-azidoethyl)- | HCID 145976 | — |
| Catalyst | Chlororuthenium(1+) 1,2,3,4,5-pentamethylcyclopenta-2,4-dien-1-ide--triphenylphosphane (1/1/2) | HCID 71310463 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 1-phenethyl-5-phenyl-1H-1,2,3-triazole | HCID 68431940 | 89% |
Reaction Steps
Phenethyl azide (148 mg, 1 mmol), phenylacetylene (113 mg, 1.1 mmol), Cp*RuCl(PPh3)2 (8 mg, 0.01 mmol, 1 mol %). Solvent: THF, 10 mL, 60° C., 2 hours. Off-white product obtained in 89% yield (221 mg). ESI-MS: m/z 250, [M+H].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08372986B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-4904ba8c1f55414f801ba6c95f0974fa |
| Source note | uspto-grants-2013_02 |