反应详情

tert-Butyl 4-(5-cyclopropyl-3-ethynyl-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)piperazine-1-carboxylate (200 mg, 0.4 mmol) was placed in MeOH (2 mL). Pd/C (175 mg, 0.08 mmol) was then added, and the reaction was stirred at room temperature for 1 hour. The reaction was then filtered and concentrated to give tert-butyl 4-(5-cyclopropyl-3-ethyl-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)piperazine-1-carboxylate (150 mg, 74% yield).

1. filtrationThe reaction was then filtered
2. concentrationconcentrated