Sulfuric Acid → 8-(2-Methoxy-4-aminocarbonyl-phenyl)-3H-purin-2-one

HRID 3876Notes

Reaction equation

HRID 3876 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([C:9]#[N:10])[CH:6]=[CH:5][C:4]=1[C:11]1[NH:19][C:18]2[CH:17]=[N:16][C:15](=[O:20])[NH:14][C:13]=2[N:12]=1.S(=O)(=O)(O)[OH:22]>>[CH3:1][O:2][C:3]1[CH:8]=[C:7]([C:9]([NH2:10])=[O:22])[CH:6]=[CH:5][C:4]=1[C:11]1[NH:19][C:18]2[CH:17]=[N:16][C:15](=[O:20])[NH:14][C:13]=2[N:12]=1

Participants

3

Reactant 2

HCID 1118Sulfuric AcidHCID 20153314HCID 20153314, compound

Product 1

HCID 201532338-(2-Methoxy-4-aminocarbonyl-phenyl)-3H-purin-2-one

Procedure

Prepared by partial saponification of 8-(2-methoxy-4-cyanophenyl)-3H-purin-2-one with concentrated sulfuric acid at ambient temperature.

Sources & evidence

ORD record
ord-c7a439da589547019f39681016779e11
Source dataset
uspto-grants-1988_02
Patent number
US04722929

Reaction notes

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