HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl acetate hexane → phenyl N-(3-fluoropropyl)carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl acetate hexane | HCID 21226206 | — |
| Reactant | 3-Fluoropropan-1-amine hydrochloride | HCID 21907455 | — |
| Product | phenyl N-(3-fluoropropyl)carbamate | HCID 22936322 | 29.42% |
Reaction Steps
3-Fluoropropylamine hydrochloride (0.92 g (wet), 8.10 mmol) was used for reaction in the same manner as Production Example 310-1, and purification was performed by silica gel column chromatography (hexane/ethyl acetate system) to obtain the title compound (0.470 g, 2.3832 mmol, 29.42%) as pink crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08372981B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-0c184b9ee22f415a9a1d619c181252cf |
| Source note | uspto-grants-2013_02 |