Benzeneacetamide → (+/-)-Trans-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1yl)-4-phenyl-pyrrolidine-2,5-dione

참여 물질

역할	이름	HCID	투입량
반응물	Benzeneacetamide	HCID 7680	—
반응물	2-(2-Chloro-4-fluorophenyl)acetamide	HCID 2773716	—
생성물	(+/-)-Trans-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1yl)-4-phenyl-pyrrolidine-2,5-dione	HCID 86608200	—

반응 단계

(±)-Trans-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1yl)-4-phenyl-pyrrolidine-2,5-dione was prepared according to the Example 40 replacing 2-chloro-4-fluorophenylacetamide with phenylacetamide. 1H NMR (DMSO-d6) 400 MHz δ: 11.511 (s, 1H), 7.24-7.36 (m, 6H), 7.13 (d, 1H, J=7.2), 6.8-6.88 (m, 2H), 4.49 (d, 1H, J=8.0 Hz), 4.3 (d, 1H, J=7.6 Hz), 4.08 (m, 2H), 2.88 (m, 2H), 2.088 (m, 2H).

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US08377927B2
출처 데이터셋	uspto-grants-2013_02
ORD ID	ord-fa8f32c052fc4c4f8124cd515f47f81b
출처 메모	uspto-grants-2013_02