Sulfuric acid magnesium salt (1:1) → 3-[(3-Amino-2-chloroquinolin-4-yl)amino]propan-1-ol

関与物質

反応手順

The method of Part B of Example 1 was used to hydrogenate 3-[(2-chloro-3-nitroquinolin-4-yl)amino]propan-1-ol (10.0 g, 35.5 mmol) with the modifications that the reaction was stopped after one hour, and magnesium sulfate was added to the mixture before filtration. 3-[(3-Amino-2-chloroquinolin-4-yl)amino]propan-1-ol (10 g) was isolated as an amber oil and was combined with material made in separate experiments.

情報源と証拠