HuagongsheHuagongshe Chemistry Print Report · For research reference only
cis-4-Hydroxy-piperidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester → HCID 66730327, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | cis-4-Hydroxy-piperidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester | HCID 14890235 | — |
| Reactant | N-Cbz-{4-[7-methoxy-8-methyl-2-(4-trifluoromethyl-thiazol-2-yl)-quinolin-4-yloxy]}-piperidine-2-carboxylic acid methyl ester | HCID 66730320 | — |
| Product | HCID 66730327 | HCID 66730327 | 60% |
Reaction Steps
Compound 22 was synthesized from compounds 12 and 206 as a yellow powder in 60% yield according to the procedure as described for compound 13. MS (ESI, EI+) m/z=617 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08377962B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-8a2650812ce34c5a804582c3646d10b8 |
| Source note | uspto-grants-2013_02 |