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HRID388662

反应详情

EQUATION

反应方程式

HRID 388662 的结构方程式

REACTANTS

反应物

3
结构：COc1ccc(C(C)=O)c(NC(=O)c2nc(C(C)C)cs2)c1
HCID20773655

N-(2-Acetyl-5-methoxyphenyl)-4-(1-methylethyl)-2-thiazolecarboxamide

C16H18N2O3S

结构：COc1ccc(C(C)=O)c(N)c1F
HCID44203147

未命名化合物

结构：CC(C)c1csc(C(=O)Cl)n1
HCID57578796

4-(Propan-2-yl)-1,3-thiazole-2-carbonyl chloride

C7H8ClNOS

PRODUCTS

生成物

1
结构：COc1ccc(C(C)=O)c(NC(=O)c2nc(C(C)C)cs2)c1F
HCID66650494

未命名化合物

收率 84%

PROCEDURE

实验过程

N-(6-Acetyl-2-fluoro-3-methoxyphenyl)-4-isopropylthiazole-2-carboxamide 217c was synthesized from 1-(2-amino-3-fluoro-4-methoxyphenyl)ethanone and compound 214 as a beige solid in 84% yield, according to the procedure as described for compound 217a. MS (ESI, EI+): m/z=337 (MH+).