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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 388667Generated: October 29, 2026

N-(6-Acetyl-3-methoxy-2-methylphenyl)-4-(propan-2-yl)-1,3-thiazole-2-carboxamide → 2-(4-Isopropylthiazol-2-YL)-7-methoxy-8-methylquinolin-4-OL

https://huagongshe.com/reaction/388667

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(6-Acetyl-3-methoxy-2-methylphenyl)-4-(propan-2-yl)-1,3-thiazole-2-carboxamideHCID 53482122—
ReactantHCID 178487691HCID 178487691—
Product2-(4-Isopropylthiazol-2-YL)-7-methoxy-8-methylquinolin-4-OLHCID 17848769260%

Reaction Steps

2-(4-Isopropylthiazol-2-yl)-7-methoxy-8-methylquinolin-4-ol 218b was synthesized from compound 217b as a yellow solid in 60% yield, according to the procedure as described for compound 218a. MS (ESI, EI+): m/z=315 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08377962B2
Source datasetuspto-grants-2013_02
ORD IDord-f816dbcd5c414d9b8a0d324299b1e2ec
Source noteuspto-grants-2013_02