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HRID388721

反应详情

EQUATION

反应方程式

HRID 388721 的结构方程式

REACTANTS

反应物

2
结构：COC(=O)[C@@]12C[C@H]1C=CCCCCN(C)C(=O)N1CC[C@H](Oc3cc(-c4nc(C)cs4)nc(-c4nc(C(F)(F)F)cs4)n3)C[C@H]1C(=O)N2
HCID68501381

未命名化合物

结构：C#Cc1csc(-c2cc(O[C@@H]3CCN4C(=O)N(C)CCCC/C=C\[C@@H]5C[C@@]5(C(=O)O)NC(=O)[C@@H]4C3)c3ccc(OC)c(C)c3n2)n1
HCID87472044

未命名化合物

PRODUCTS

生成物

1
结构：Cc1csc(-c2cc(O[C@H]3CCN4C(=O)N(C)CCCCC=C[C@@H]5C[C@@]5(C(=O)O)NC(=O)[C@@H]4C3)nc(-c3nc(C(F)(F)F)cs3)n2)n1
HCID91281201

未命名化合物

收率 82%

PROCEDURE

实验过程

(1S,4R,6S,18S)-18 [6-(4-Methylthiazol-2-yl)-2-(4-trifluoromethylthiazol-2-yl)-pyrimidin-4-yloxy]-13-N-methyl-2,14-dioxo-3,13,15-triazatricyclo[13.4.0.0*4,6*]nonadec-7-ene-4-carboxylic acid 42b was synthesized from compound 41b (250 mg, 1.0 eq.), according to the procedure as described for compound 38, as a green foam in 82% yield. MS (ESI, EI−) m/z=690 (MH−).