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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 388798Generated: October 29, 2026

2-Fluoro-4-iodoaniline → 5-Chloro-N-((1-(2-fluoro-4-iodophenyl)-1H-1,2,3-triazol-4-yl)methyl)thiophene-2-carboxamide

https://huagongshe.com/reaction/388798

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-4-iodoanilineHCID 185694—
Reactant5-Chloro-N-((1-(4-(2-oxopyridin-1(2H)-yl)phenyl)-1H-1,2,3-triazol-4-yl)methyl)thiophene-2-carboxamideHCID 57640505—
Product5-Chloro-N-((1-(2-fluoro-4-iodophenyl)-1H-1,2,3-triazol-4-yl)methyl)thiophene-2-carboxamideHCID 57640764—

Reaction Steps

The title compound was prepared by the same procedure for compound 35 described in Example 290 in Scheme 5, using 4-iodo-2-fluoroaniline in place of 4-iodoaniline. MS found for C14H9ClFIN4OS as (M+H)+ 462.0, 464.0

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08377974B2
Source datasetuspto-grants-2013_02
ORD IDord-a3649b51cef64e4aae791ee25dd811ad
Source noteuspto-grants-2013_02