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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 388945Generated: October 25, 2026

Hydrochloric Acid → HCID 178521765, compound

https://huagongshe.com/reaction/388945

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 178452214HCID 178452214—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 178521765HCID 178521765—

Reaction Steps

The product from Example 87 was treated with 4M HCl in dioxane employing the procedure described for Example 80 to afford of 6-piperazin-1-yl-2-(2-trifluoromethylphenylamino)-1H-benzimidazole-5-carboxylic acid (1H-indazol-6-yl)-amide as a hydrochloride salt. MS: m/z 521 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08377983B2
Source datasetuspto-grants-2013_02
ORD IDord-84a14b4db27e4a7abce1a04981199b5f
Source noteuspto-grants-2013_02