Lithium Hydroxide → HCID 86647502, compound

Participants

Reaction Steps

LiOH (66 mmol) was added to a solution of ethyl (2S)-2-({[(2,2-dimethylpent-4-en-1-yl)(methyl)amino]carbonyl}amino)non-8-enoate (2.35 g, 6.67 mmol) in MeOH (20 mL), water (10 mL) and THF (30 mL). The reaction mixture was stirred for 3 hours at RT and then concentrated. A solution 5% potassium bisulfate was added, and the mixture was extracted with EtOAc (3×). The combined organic were washed with brine, dried over MgSO4, filtered and concentrated to give the title compound. LRMS (M+H)+=325.3.

Provenance & Evidence