関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 1,2-Dichlorobenzene | HCID 7239 | — |
| 反応物 | 6-Bromohexanoic acid | HCID 20210 | — |
| 反応物 | 5-Methoxy-2,3,3-trimethyl-3H-indole | HCID 11095392 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | 1-(5-carboxypentyl)-5-methoxy-2,3,3-trimethyl-3H-indolium bromide | HCID 68816685 | 80.9% |
反応手順
To 5-methoxy-2,3,3-trimethyl-3H-indole (1.9 g) was added 6-bromohexanoic acid (3 g) and 1,2-dichlorobenzene (10 ml). The mixture was heated to 10° C. for 3 hours and then allowed to cool to room temperature. Diethyl ether was added and the precipitated material removed by filtration. Drying in a vacuum oven gave the product (3.12 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08378120B2 |
|---|
| 出典データセット | uspto-grants-2013_02 |
|---|
| ORD ID | ord-08752a76977a4ffdb8415baf6b48d1da |
|---|
| 出典メモ | uspto-grants-2013_02 |
|---|
