HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 389243Generated: October 29, 2026
1-Bromo-3,6-dioxaheptane → 3-(5-carboxypentyl)-1-(2-(2-methoxyethoxy)ethyl)-2,3-dimethyl-3H-indolium bromide
https://huagongshe.com/reaction/389243
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-Bromo-3,6-dioxaheptane | HCID 123532 | — |
| Reactant | 6-(2,3-dimethyl-3H-indol-3-yl)hexanoic acid | HCID 57937748 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 3-(5-carboxypentyl)-1-(2-(2-methoxyethoxy)ethyl)-2,3-dimethyl-3H-indolium bromide | HCID 68813228 | — |
Reaction Steps
To 6-(2,3-dimethyl-3H-indol-3-yl)hexanoic acid (100 mg) was added 1-bromo-2-(2-methoxyethoxy)ethane (1 ml) and the mixture heated to 90° C. overnight. On cooling diethyl ether (10 ml) was added and the material removed by filtration.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08378120B2 |
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| Source dataset | uspto-grants-2013_02 |
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| ORD ID | ord-5f8cbcc5d3e24025af15ed443a33a142 |
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| Source note | uspto-grants-2013_02 |
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