HuagongsheHuagongshe Chemistry Print Report · For research reference only
Allylamine → N-{[5-Fluoro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-YL]methyl}prop-2-EN-1-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Allylamine | HCID 7853 | — |
| Reactant | [5-Fluoro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl 4-methylbenzenesulfonate | HCID 86652936 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | N-{[5-Fluoro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-YL]methyl}prop-2-EN-1-amine | HCID 44469878 | — |
Reaction Conditions
| Temperature | 120 °C |
|---|
Reaction Steps
A mixture of [5-fluoro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl-4-methylbenzenesulfonate (0.005 g, 0.012 mmol), prop-2-en-1-amine (0.5 ml) and ACN (2.5 ml) was heated under microwave radiation at 120° C. for 20 min. MS m/z (rel. intensity, 70 eV) 301 (M+, 2), 71 (5) 70 (bp), 69 (4) 68 (5).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08524766B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-42477169d453425ca2e247d102ddb151 |
| Source note | uspto-grants-2013_09 |