[4-Methoxy-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-acetic acid ethyl ester → HCID 58579972, compound

HRID 389269Notes

Reaction equation

HRID 389269 reaction equation
[C:1]([O:5][C:6](=[O:19])[N:7]([CH2:10][C:11]1[C:12](Cl)=[N:13][CH:14]=[C:15]([CH3:17])[CH:16]=1)[CH2:8][CH3:9])([CH3:4])([CH3:3])[CH3:2].[CH2:20]([O:22][C:23](=[O:42])[CH2:24][C:25]1[CH:30]=[CH:29][C:28]([O:31][CH3:32])=[C:27](B2OC(C)(C)C(C)(C)O2)[CH:26]=1)[CH3:21]>>[CH2:20]([O:22][C:23](=[O:42])[CH2:24][C:25]1[CH:30]=[CH:29][C:28]([O:31][CH3:32])=[C:27]([C:12]2[C:11]([CH2:10][N:7]([C:6]([O:5][C:1]([CH3:4])([CH3:3])[CH3:2])=[O:19])[CH2:8][CH3:9])=[CH:16][C:15]([CH3:17])=[CH:14][N:13]=2)[CH:26]=1)[CH3:21]

Participants

3

Reactant 2

HCID 58120060[4-Methoxy-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-acetic acid ethyl esterHCID 58579974HCID 58579974, compound

Product 1

HCID 58579972HCID 58579972, compound

Procedure

Prepared according to the procedure described in Example 2, Step 6, using the following starting materials: (2-chloro-5-methyl-pyridin-3-ylmethyl)-ethyl-carbamic acid tert-butyl ester and [4-methoxy-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-acetic acid ethyl ester.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-49450f1688e04ea1a82a12b565c21c92
Source dataset
uspto-grants-2013_02
Patent number
US08378107B2

Reaction notes

Loading…