Acetic Anhydride → HCID 58579971, compound

HRID 389279Notes

Reaction equation

HRID 389279 reaction equation
[CH2:1]([O:3][C:4](=[O:28])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([C:14]2[C:23]([CH2:24][NH:25][CH2:26][CH3:27])=[CH:22][C:21]3[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=3)[N:15]=2)[CH:7]=1)[CH3:2].C1(N)C(F)=C(F)C(F)=C(N)C=1F.Cl.Cl.[C:43](OC(=O)C)(=[O:45])[CH3:44]>>[CH2:1]([O:3][C:4](=[O:28])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([C:14]2[C:23]([CH2:24][N:25]([C:43](=[O:45])[CH3:44])[CH2:26][CH3:27])=[CH:22][C:21]3[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=3)[N:15]=2)[CH:7]=1)[CH3:2]

Participants

4

Reactant 3

HCID 7918Acetic AnhydrideHCID 149026Tetrafluoro-m-phenylenediamine dihydrochlorideHCID 58579978HCID 58579978, compound

Product 1

HCID 58579971HCID 58579971, compound

Procedure

Prepared according to the procedure described in Example 5, Step 5, using the following starting materials: [3-(3-ethylaminomethyl-quinolin-2-yl)-4-methoxy-phenyl]-acetic acid ethyl ester; dihydrochloride and acetic anhydride.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-160be2d4add747179b7773e3faeec112
Source dataset
uspto-grants-2013_02
Patent number
US08378107B2

Reaction notes

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