Methoxyacetyl chloride → HCID 58579963, compound

HRID 389280Notes

Reaction equation

HRID 389280 reaction equation
[CH2:1]([O:3][C:4](=[O:28])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([C:14]2[C:23]([CH2:24][NH:25][CH2:26][CH3:27])=[CH:22][C:21]3[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=3)[N:15]=2)[CH:7]=1)[CH3:2].C1(N)C(F)=C(F)C(F)=C(N)C=1F.Cl.Cl.[CH3:43][O:44][CH2:45][C:46](Cl)=[O:47]>>[CH2:1]([O:3][C:4](=[O:28])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([C:14]2[C:23]([CH2:24][N:25]([CH2:26][CH3:27])[C:46](=[O:47])[CH2:45][O:44][CH3:43])=[CH:22][C:21]3[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=3)[N:15]=2)[CH:7]=1)[CH3:2]

Participants

4

Reactant 3

HCID 96623Methoxyacetyl chlorideHCID 149026Tetrafluoro-m-phenylenediamine dihydrochlorideHCID 58579978HCID 58579978, compound

Product 1

HCID 58579963HCID 58579963, compound

Procedure

Prepared according to the procedure described in Example 5, Step 5, using the following starting materials: [3-(3-ethylaminomethyl-quinolin-2-yl)-4-methoxy-phenyl]-acetic acid ethyl ester; dihydrochloride and methoxyacetyl chloride.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-15496b0da48e48b68c4bd093b4cbec9f
Source dataset
uspto-grants-2013_02
Patent number
US08378107B2

Reaction notes

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