[4-Methoxy-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-acetic acid ethyl ester → HCID 58579977, compound

HRID 389283Notes

Reaction equation

HRID 389283 reaction equation
[C:1]([O:5][C:6](=[O:22])[N:7]([CH2:10][C:11]1[C:20](Br)=[CH:19][C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[N:12]=1)[CH2:8][CH3:9])([CH3:4])([CH3:3])[CH3:2].[CH2:23]([O:25][C:26](=[O:45])[CH2:27][C:28]1[CH:33]=[CH:32][C:31]([O:34][CH3:35])=[C:30](B2OC(C)(C)C(C)(C)O2)[CH:29]=1)[CH3:24]>>[CH2:23]([O:25][C:26](=[O:45])[CH2:27][C:28]1[CH:33]=[CH:32][C:31]([O:34][CH3:35])=[C:30]([C:20]2[C:11]([CH2:10][N:7]([C:6]([O:5][C:1]([CH3:4])([CH3:3])[CH3:2])=[O:22])[CH2:8][CH3:9])=[N:12][C:13]3[C:18]([CH:19]=2)=[CH:17][CH:16]=[CH:15][CH:14]=3)[CH:29]=1)[CH3:24]

Participants

3

Reactant 2

HCID 58120060[4-Methoxy-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-acetic acid ethyl esterHCID 58579975HCID 58579975, compound

Product 1

HCID 58579977HCID 58579977, compound

Procedure

Prepared according to the procedure described in Example 5, Step 3, using the following starting materials: (3-bromo-quinolin-2-ylmethyl)-ethyl-carbamic acid tert-butyl ester and [4-methoxy-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-acetic acid ethyl ester.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-624f32bd61b143b9bc9d213d7f3043b3
Source dataset
uspto-grants-2013_02
Patent number
US08378107B2

Reaction notes

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