HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → 1-[5-Fluoro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-YL]-N,N-dimethylmethanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | [5-Fluoro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl 4-methylbenzenesulfonate | HCID 86652936 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 1-[5-Fluoro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-YL]-N,N-dimethylmethanamine | HCID 44470295 | — |
Reaction Steps
Preparation according to Example 42 using [5-fluoro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl-4-methylbenzenesulfonate (0.005 g, 0.012 mmol), N-methylmethanamine (0.5 ml, 2.0 M in MeOH), ACN (2.5 ml). MS m/z (rel. intensity, 70 eV) 289 (M+, 1), 84 (2), 69 (2), 59 (3), 58 (bp).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08524766B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-6f691840cfb042a6b1e301f9fa0a7760 |
| Source note | uspto-grants-2013_09 |