Ethanol → HCID 51002954, compound

Participants

Reaction Steps

A heavy-walled glass tube was charged with ethyl (S,SS)-2-[1-(tert-butylsulfinylamino)butyl]-1,3-dithiolane-2-carboxylate (0.50 g, 1.4 mmol) and a chilled 8.0 M solution of methylamine in ethanol (5 mL, 40 mmol). The mixture was allowed to warm to room temperature and was allowed to stand for 72 hours. Distillation of the solvent at reduced pressure afforded (S,SS)-2-[1-(tert-butylsulfinylamino)butyl]-N-methyl-1,3-dithiolane-2-carboxamide (0.47 g, 98%) as a viscous amber-colored oil.

Provenance & Evidence