HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Propanamine, N-ethyl- → N-Ethyl-N-{[5-fluoro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-YL]methyl}propan-1-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Propanamine, N-ethyl- | HCID 88398 | — |
| Reactant | [5-Fluoro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl 4-methylbenzenesulfonate | HCID 86652936 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | N-Ethyl-N-{[5-fluoro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-YL]methyl}propan-1-amine | HCID 44470158 | — |
Reaction Steps
Preparation according to Example 42 using [5-fluoro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl-4-methylbenzenesulfonate (0.005 g, 0.012 mmol), N-ethylpropan-1-amine (0.5 ml), ACN (2.5 ml). MS m/z (rel. intensity, 70 eV) 331 (M+, 0.5), 101 (7), 100 (bp), 98 (8), 58 (8).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08524766B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-faf9560b7cf54d9ea4dde547e8d0ddf3 |
| Source note | uspto-grants-2013_09 |