反应详情

Preparation according to Example 42 using [5-fluoro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl-4-methylbenzenesulfonate (0.005 g, 0.012 mmol), 2-aminoethanol (0.5 ml), ACN (2.5 ml). 1H-NMR (400 MHz, MeOD): δ 7.36 (2H, m), δ 4.54 (1H, dd, J 12, 2.4), δ 4.44 (1H, m), δ 4.18 (1H, dd, J 12, 7.2), δ 3.71 (2H, t, J 5.6), δ 3.13 (3H, s), δ 2.98 (2H, m), 2.81 (2H, m) ppm (J-values are in Hz and shifts relative to solvent-peak at 3.31 ppm).

1. customPreparation