Allylamine → N-{[(2S)-5-Chloro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-YL]methyl}prop-2-EN-1-amine

Participants

Role	Name	HCID	Charge
Reactant	Allylamine	HCID 7853	—
Reactant	[(2R)-5-chloro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl 4-methylbenzenesulfonate	HCID 86652939	—
Solvent	Acetonitrile	HCID 6342	—
Product	N-{[(2S)-5-Chloro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-YL]methyl}prop-2-EN-1-amine	HCID 44470296	—

Reaction Conditions

Temperature	120 °C

Reaction Steps

A mixture of [(2R)-5-chloro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl 4-methylbenzenesulfonate (0.027 g, 0.062 mmol), prop-2-en-1-amine (0.5 ml) and ACN (3 ml) was heated under microwave radiation at 120° C. for 20 min. MS m/z (rel. intensity, 70 eV) 317 (M+, 2), 113 (3), 71 (5), 70 (bp), 68 (3) 63 (3).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08524766B2
Source dataset	uspto-grants-2013_09
ORD ID	ord-942f4598d331407a8c700dcd3b174e4e
Source note	uspto-grants-2013_09