4-Iodo-2-(isoquinolin-5-yl)furo[2,3-c]pyridin-7-amine → 2-(1,2-Benzothiazol-7-yl)-4-iodofuro[2,3-c]pyridin-7-amine

Participants

Role	Name	HCID	Charge
Reactant	4-Iodo-2-(isoquinolin-5-yl)furo[2,3-c]pyridin-7-amine	HCID 66759474	—
Reactant	2-(1,2-Benzothiazol-7-yl)furo[2,3-c]pyridin-7-amine	HCID 66759632	—
Product	2-(1,2-Benzothiazol-7-yl)-4-iodofuro[2,3-c]pyridin-7-amine	HCID 66761024	92%

Reaction Steps

The title compound was prepared in 92% yield from 2-(1,2-benzothiazol-7-yl)furo[2,3-c]pyridin-7-amine by a procedure analogous to Intermediate 10, Step B. 1H NMR (300 MHz, CDCl3): δ 4.62 (br. s, 2H), 7.13 (s, 1H), 7.73 (t, J=5.7 Hz, 1H), 7.98 (s, 1H), 8.35-8.45 (m, 2H), 9.28 (s, 1H).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08378104B2
Source dataset	uspto-grants-2013_02
ORD ID	ord-81a327998ca44c2482678fb9b4b176b7
Source note	uspto-grants-2013_02