HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Cyclohexanediol → 3-(Tert-butyldimethylsilyl)oxy-1-cyclohexanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Cyclohexanediol | HCID 10433 | — |
| Reactant | 2-[3-(tert-butyldimethylsilanyloxy)-cyclopentyl]-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole | HCID 66759519 | — |
| Product | 3-(Tert-butyldimethylsilyl)oxy-1-cyclohexanol | HCID 557077 | 35% |
Reaction Steps
The title compound was prepared in 35% yield from 1,3-cyclohexanediol by a procedure analogous to Intermediate 28, Step A. 1H NMR (300 MHz, CDCl3): δ 4.0-4.2 (m, 1H), 3.8-3.95 (m, 1H), 1.3-2.4 (m, 9H), 0.86 (s, 9H), 0.05 (s, 6H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08378104B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-952be78ea2404a4b9f2eea420bff95c3 |
| Source note | uspto-grants-2013_02 |