Ethanolamine → HCID 44468240, compound

Participants

Reaction Steps

Preparation according to Example 57 using [(2R)-5-chloro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl 4-methylbenzenesulfonate (0.027 g, 0.062 mmol), 2-aminoethanol (0.5 ml), ACN (3 ml). 1H-NMR (400 MHz, MeOD): δ 7.57 (1H, d, J 2.3), δ 7.46 (1H, d, J 2.3), δ 4.59 (1H, dd, J 11.6, 2.4), δ 4.42 (1H, m), δ 4.21 (1H, dd, J 11.6, 7.4), δ 3.71 (2H, t, J 5.3), δ 3.14 (3H, s), δ 2.97 (2H, d, J 5.8), δ 2.82 (3H, m) ppm (J-values are in Hz and shifts relative to solvent-peak at δ 4.8 ppm).

Provenance & Evidence