HCID 53377966, compound → HCID 53378066, compound

Participants

Reaction Steps

A suspension of 4-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]-2-(1,2,3,6-tetrahydropyridin-4-yl)furo[2,3-c]pyridin-7-amine (30 mg, 0.082 mmol) and 10% Pd/C (5 mg) in MeOH (10 mL) was stirred at RT under a H2 balloon for 2 h. The reaction mixture was filtered and concentrated to afford the title compound. 1H NMR (400 MHz, CD3OD): δ 8.29 (s, 1H), 7.89 (s, 1H), 7.73 (s, 1H), 7.19 (s, 1H), 4.62 (m, 1H), 3.49 (m, 4H), 3.34 (m, 1H), 3.15 (m, 4H), 2.29 (m, 6H), 2.07 (m, 2H); MS (ESI): 367.1 [M+H]+.

Provenance & Evidence