N-Methylethylamine → N-{[(2S)-5-Chloro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-YL]methyl}-N-methylethanamine

Participants

Role	Name	HCID	Charge
Reactant	N-Methylethylamine	HCID 12219	—
Reactant	[(2R)-5-chloro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl 4-methylbenzenesulfonate	HCID 86652939	—
Solvent	Acetonitrile	HCID 6342	—
Product	N-{[(2S)-5-Chloro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-YL]methyl}-N-methylethanamine	HCID 44468244	—

Reaction Steps

Preparation according to Example 57 using [(2R)-5-chloro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl 4-methylbenzenesulfonate (0.027 g, 0.062 mmol), N-methylethanamine (0.5 ml), ACN (3 ml). MS m/z (rel. intensity, 70 eV) 319 (M+, 0.3), 85 (3), 84 (3), 73 (5), 72 (bp), 63 (2).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08524766B2
Source dataset	uspto-grants-2013_09
ORD ID	ord-0b11b57e306f4930a0001484a8ee8958
Source note	uspto-grants-2013_09