Neopentylamine → N-{[(2S)-5-Chloro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-YL]methyl}-2,2-dimethylpropan-1-amine

Participants

Role	Name	HCID	Charge
Reactant	Neopentylamine	HCID 79882	—
Reactant	[(2R)-5-chloro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl 4-methylbenzenesulfonate	HCID 86652939	—
Solvent	Acetonitrile	HCID 6342	—
Product	N-{[(2S)-5-Chloro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-YL]methyl}-2,2-dimethylpropan-1-amine	HCID 44468241	—

Reaction Steps

Preparation according to Example 57 using [(2R)-5-chloro-7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl 4-methylbenzenesulfonate (0.027 g, 0.062 mmol), 2,2-dimethylpropan-1-amine (0.5 ml), ACN (3 ml). MS m/z (rel. intensity, 70 eV) 347 (M+, 2), 332 (20), 292 (30), 290 (78), 100 (bp), 70 (16).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08524766B2
Source dataset	uspto-grants-2013_09
ORD ID	ord-af60aa299cb94b17ab8bb06df3f38305
Source note	uspto-grants-2013_09