Methylamine → HCID 85873295, compound

Participants

Reaction Conditions

Reaction Steps

7-Bromo-2-chlorobenzothiazole (85 mg, 0.34 mmol) and methylamine (2 M in THF, 3 mL, 6 mmol) were mixed and heated to 60° C. overnight. The solvent was evaporated. The residue was purified by ISCO chromatography (0 to 30% EtOAc:heptane) to afford 56 mg (67%) of the title compound. MS (ESI): 243.30, 245.26 [M+H]+; HPLC tR=1.09 min (HPLC: Anayltical—2 min).

Provenance & Evidence