Sulfuryl chloride → 2-Chloro-3-(3-oxomorpholino)benzene-1-sulfonyl chloride

HRID 389651Notes

Reaction equation

C(S[C:9]1[C:10]([Cl:22])=[C:11]([N:15]2[CH2:20][CH2:19][O:18][CH2:17][C:16]2=[O:21])[CH:12]=[CH:13][CH:14]=1)C1C=CC=CC=1.[S:23]([Cl:27])(Cl)(=[O:25])=[O:24]>>[Cl:22][C:10]1[C:11]([N:15]2[CH2:20][CH2:19][O:18][CH2:17][C:16]2=[O:21])=[CH:12][CH:13]=[CH:14][C:9]=1[S:23]([Cl:27])(=[O:25])=[O:24]

Participants

Reactant 2

HCID 24648Sulfuryl chloride

HCID 669111644-(3-(Benzylthio)-2-chlorophenyl)morpholin-3-one

Product 1

HCID 727929542-Chloro-3-(3-oxomorpholino)benzene-1-sulfonyl chloride

Procedure

Intermediate 17 (1 g, 3.05 mmol) was converted to the title sulfonyl chloride using the procedure described in 1.7). The crude material was used without further purification in the next step.

Workup

customThe crude material was used without further purification in the next step

Sources & evidence

ORD record: ord-e50177b8f36747a3866f1aa156c749f9
Source dataset: uspto-grants-2013_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08378092B2

Reaction notes

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