Hydrochloric Acid → HCID 67155454, compound

Participants

Reaction Steps

Intermediate 81 (1.08 g, 2.12 mmol) was dissolved in 20 ml of THF and sodium hydroxide (1 N water solution) (4.24 ml, 4.24 mmol) was added. After 16 h stirring at RT 1 N HCl (9 ml) was added, solvents were evaporated and n-butanol was added. The organic layer was dried with Na2SO4, filtered and evaporated to dryness. 1.05 g (yield: 99%) of crude product. The intermediate was directly used in the next step.

Provenance & Evidence