Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Bromo-1-(4-fluorophenyl)ethan-1-one → 1-(4-Fluorophenyl)-2-hydroxyethanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Bromo-1-(4-fluorophenyl)ethan-1-one | HCID 96749 | — |
| 반응물 | Sodium Formate | HCID 2723810 | — |
| 용매 | Water ethanol | HCID 19096565 | — |
| 생성물 | 1-(4-Fluorophenyl)-2-hydroxyethanone | HCID 2810715 | — |
반응 단계
2 g of 2-bromo-1-(4-fluorophenyl)ethanone, and 6 eq of sodium formate in 15 mL of Ethanol/Water are irradiated under microwave for 5 min at 150° C., 11 bars. After filtration and evaporation of ethanol, water is added. The expected product is isolated by filtration
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08383608B2 |
| 출처 데이터셋 | uspto-grants-2013_02 |
| ORD ID | ord-8b4c3b7374b442a791bc292e57fcc1b1 |
| 출처 메모 | uspto-grants-2013_02 |