HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 389886Generated: October 31, 2026
Ethanol → 3-[2,5-Dioxo-4-[(2-propenyloxy)methyl]imidazolidin-4-yl]benzonitrile
https://huagongshe.com/reaction/389886
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Potassium Cyanide | HCID 9032 | — |
| Reactant | Ammonium Carbonate | HCID 517111 | — |
| Reactant | (2-(2-Propenyloxy)acetyl]benzonitrile | HCID 86641460 | — |
| Product | 3-[2,5-Dioxo-4-[(2-propenyloxy)methyl]imidazolidin-4-yl]benzonitrile | HCID 67131009 | — |
Reaction Steps
To a solution of 450 mg of 3-[(2-(2-propenyloxy)acetyl]benzonitrile (in EtOH (5 mL) and water (5 mL) 291 mg of potassium cyanide and ammonium carbonate are added. The mixture is refluxed one night at 55° C. The mixture is extracted with ethyl acetate, dried over magnesium sulfate and concentrated under vacuum to give the desired compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08383608B2 |
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| Source dataset | uspto-grants-2013_02 |
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| ORD ID | ord-39ff7f05feeb4343b34cfb265185d649 |
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| Source note | uspto-grants-2013_02 |
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